Replying to my own thread...I wanted to share how I configure the interface with ProfitUI!
It's clean, doesn't waste rendering space (allowing very high quality graphics), runs at 1920x1200 resolution, has 3 chat windows (1 for general, 1 for private messages, and 1 for guild/group chat), and other than ProfitUI, I use EQ2MAP and a few enhancements to that...
This is what my interface looks like!
