I'm not completely sure but looking at your screenshot it looks like you're running a version that's pre v2.18.x... I'd suggest downloading the latest 'eXtreme' and run that. I haven't had that problem with the XP for a loooooong time
I actually never saw that line in my 'eq2_recent.ini' file nor did I see it in my 'eq2.ini' so what I did was this:
1) Open 'Windows Explorer' and open my 'Everquest II' folder.
2) Copy all my '.ini' files and pasted them into a new folder called 'Copy of INI Files'.
3) Logged into EQ2 with my main toon and made sure all my windows were situated the way I wanted them arranged.
4) Logged out of EQ2 and open my 'Everquest II' folder again.
5) Added the line 'cl_uisettings_file server_character_eq2_uisettings.ini' (or whatever the name is for your main toon) to my 'eq2.ini' file (Landiin's idea since he said 'eq2_recent.ini' gets overwritten by SOE)
6) Saved the file, deleted all other copies of the INI files for all my other toons except my main toon.
Now whenever I logon with any of my characters, they all use that file. Even the new toons I created us that main settings file. I love this feature