I'm pretty happy with the way mine is setup, a few things I've been moving around like my maintained window and my group / raid windows are constantly getting moved around. I need to get a new monitor so I can bump up the size of my res and start playing at 1600x1200 again, but here is the sexyness:

This is my layout; mostly ThorUI, especially since the few odd pieces I used to manually insert have been added as options in ThorUI. I like having evrything easily at my fingertips, hence the busy lower section, while keeping an open forward view. Happily I'm blessed with a 1600x1200 display which makes it easy to fit everything, with enough open space around and between that I don't feel like I"m looking through a porthole.